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IGF‑IR
Summary
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Curated Studies
Most Correlated Studies
Human SK-N-AS neuroblastoma treated with anti-IGR-IR antibody
MCF-7 breast cancer cells treated with estradiol
Ewing sarcoma TC-71 derived cell lines resistant to anti-IGF-1R drugs
Lung cancer HCC827 cells showing sensitivity or acquired resistance upon gefitinib exposure
Cardiac growth - constitutive and dominant negative PI3K heart
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Literature
Most Relevant Literature
IGF‑IR promotes clonal cell proliferation in myelodysplastic syndromes via inhibition of the MAPK pa…
Effects of starter feeding and early weaning on developmental expressions of IGF-I gene in liver and…
Biglycan Interacts with Type I Insulin-like Receptor (IGF-IR) Signaling Pathway to Regulate Osteosar…
Identification of a Resistance Mechanism to IGF-IR Targeting in Human Triple Negative MDA-MB-231 Bre…
Fusion protein-driven IGF-IR/PI3K/AKT signals deregulate Hippo pathway promoting oncogenic cooperati…
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Clinical Trials
Most Relevant Clinical Trials
Study Of Anti-IGF-IR CP-751,871 In Patients With Solid Tumors
IGF and Other Neurotrophic Factors in Patients With Dementia
The Role of TSH Receptor, PPAR-r, IGF-1R, IGF and Cytokines in Different Stages of Graves’Ophthalmop…
IRS Proteins and Trastuzumab Resistance
Breast Cancer Chemoprevention by SOM230, an IGF-I Action Inhibitor
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