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JAK 1
Summary
General Info
Curated Studies
Most Correlated Studies
White-to-brown metabolic conversion of adipocytes by JAK inhibition
Ovarian cancer model treated with JAK inhibitor AZD1480
Epiblast stem cell expression profiles following induced JAK/STAT3 signaling
Skin biopsies of atopic dermatitis patients treated with oral dual JAK/SYK inhibitor ASN002
Neonatal cardiomyocytes and HL-1 cardiomyocyte cells exposed to inflammatory stimuli
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Literature
Most Relevant Literature
Efficacy of JAK1/2 inhibition in murine immune bone marrow failure.
Preferential Inhibition of JAK1 Relative to JAK3 by Upadacitinib: Exposure-Response Analyses of Ex V…
Cerebrospinal fluid neopterin as a biomarker of treatment response to Janus kinase inhibition in Aic…
Primary analysis of JUMP, a phase 3b, expanded-access study evaluating the safety and efficacy of ru…
Different Biomarkers of Response to Treatment with Selective Jak-1 Inhibitors in Rheumatoid Arthriti…
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Clinical Trials
Most Relevant Clinical Trials
Polymorphism of Janus Kinase 1 and 2 (JAK 1&2) in Patients With Alopecia Areata
JAK 1/2 Inhibitor, Baricitinib, in the Treatment of Adult IIM
Efficacy and Safety of Selective JAK 1 Inhibitor Filgotinib in Active Rheumatoid Arthritis Patients …
Janus Kinase (JAK) Inhibitors to Preserve C-Peptide Production in New Onset Type 1 Diabetes (T1D)
JAK Inhibition in Ulcerative Colitis
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