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LINGO-1
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General Info
Body Atlas
Most Correlated Tissues
Amygdala
Temporal lobe
Hippocampus
Parietal lobe
Frontal cortex
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Disease Atlas
Most Correlated Diseases
Traumatic injury
Ulceration of intestine
Disease due to West Nile virus
Developmental disorder
Mental retardation
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Pharmaco Atlas
Most Correlated Compounds
monuron
tadalafil
Tetraethylammonium
Pyrimidines
alpha-MSH
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Knockdown Atlas
Most Correlated Gene Perturbations
Gjd2
SRA1
FOXN1
CDO1
hsa-miR-375
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Curated Studies
Most Correlated Studies
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Literature
Most Relevant Literature
Functional activity of anti-LINGO-1 antibody opicinumab requires target engagement at a secondary bi…
Anti-Lingo-1 antibody ameliorates spatial memory and synapse loss induced by chronic stress.
LINGO1 is a regulatory subunit of large conductance, Ca2+-activated potassium channels.
Anti-LINGO-1 antibody treatment improves chronic stress-induced spatial memory impairments and oligo…
LINGO-1 regulates Wnt5a signaling during neural stem and progenitor cell differentiation by modulati…
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Clinical Trials
Most Relevant Clinical Trials
BIIB033 In Acute Optic Neuritis (AON)
Safety Study of BIIB033 in Subjects With Multiple Sclerosis
Efficacy and Safety of BIIB033 (Opicinumab) as an Add-on Therapy to Disease-Modifying Therapies (DMT…
BIIB033 Single Ascending Dose Study in Healthy Volunteer Subjects
Long-Term Assessment of Remyelinating Therapy
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