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LY294002
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NextBio Summary
General Info
Genetic Markers
Most Correlated Genes
DEPP1
GPNMB
EHF
PDZRN3
IL1B
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Pathway Enrichment
Most Correlated Biogroups
organic cyclic compound binding
heterocyclic compound binding
cytosol
organic cyclic compound metabolic process
regulation of nitrogen compound metabolic process
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Curated Studies
Most Correlated Studies
Treated keratinocyte HaCaT cell line overexpressing EGFR, RELA (p65), or HRAS-VAL12D
Oncogenic PI3K mutations in cancer cells following growth factor deprivation
Breast epithelial cells that are organized and disorganized in cell culture
Embryonic EBRTcH3 stem cells with or without MYC(T58A) overexpression treated with LY294002
CD4+ T cells age and culture condition comparisons treated with rapamycin or LY 294002
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Literature
Most Relevant Literature
Pyrroloquinoline Quinine and LY294002 Changed Cell Cycle and Apoptosis by Regulating PI3K-AKT-GSK3β …
LY294002, a PI3K inhibitor, attenuates Tourette syndrome in rats.
Comprehensive attenuation of IL-25-induced airway hyperresponsiveness, inflammation and remodelling …
Inhibitory Effect of LY294002 on Proliferation of Multiple Myeloma Cells and Its Mechanism].
LY294002 prevents lipopolysaccharide‑induced hepatitis in a murine model by suppressing IκB phosphor…
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Clinical Trials
Most Relevant Clinical Trials
SF1126 for Patients With Relapsed or Refractory Neuroblastoma
Study the Expression of Annexin A1 and Its Potential Usage as a Prognostic Marker in Oral Cancer
Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML)
Study of LY3023414 for the Treatment of Recurrent or Persistent Endometrial Cancer
GDC-0941 and Cisplatin in Treating Patients With Androgen Receptor-Negative Triple Negative Metastat…
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