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Leptomycin B
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
NGFR
DUSP15
MYCL
HSPA4L
FBXO32
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Pathway Enrichment
Most Correlated Biogroups
FISCHER_DREAM_TARGETS
LEE_BMP2_TARGETS_DN
nucleoplasm
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP
heterocyclic compound binding
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Curated Studies
Most Correlated Studies
Mesenchymal stromal cells treated with extracellular vesicles and/or importazole or leptomycin B
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Literature
Most Relevant Literature
Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs…
Leptomycin B inhibits the proliferation, migration, and invasion of cultured gastric carcinoma cells…
Leptomycin B alters the subcellular distribution of CRM1 (Exportin 1).
Leptomycin B reduces primary and acquired resistance of gefitinib in lung cancer cells.
Epigallocatechin-3-gallate enhances the therapeutic effects of leptomycin B on human lung cancer a54…
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Clinical Trials
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