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QuickView for Locked nucleic acid (compound)
Most Correlated Studies
- Livers treated with toxic and severely toxic locked nucleic acid (LNA) gapmers
- Non-small cell lung cancer in vitro model response to miR-92a inhibition
- Breast cancer MDA-MB-231 cells grown in hypoxia with YBX1 shRNA and LNAs targeting tRNA fragments
- Livers of mice after treatment with miR-29a miR-29b and miR-29c inhibitor
- Breast cancer MDA-MB-231 cells with YBX1 shRNA knockdown and LNAs targeting tRNA fragments
Most Relevant Literature
- Biological activity and biotechnological aspects of locked nucleic acids.
- Antagonism of microRNA function in zebrafish embryos by using locked nucleic acid enzymes (LNAzymes)…
- Bias in topoisomerase (TOPO)-cloning of multitemplate PCR products using locked nucleic acid (LNA)-s…
- Dynamics and efficiency of hole transport in LNA:DNA hybrid diblock oligomers.
- Hole transfer in LNA and 5-Me-2'-deoxyzebularine-modified DNA.
Most Relevant Clinical Trials
- Phase 1 Study of EZN-2968 Weekly in Adult Patients With Advanced Solid Tumors or Lymphoma
- Long-term Efficacy and Safety of OLE LIB003 in HoFH, HeFH, and High-risk CVD Patients Requiring Furt…
- Trial to Evaluate Efficacy and Safety of LIB003, Evolocumab and Alirocumab in High-risk CVD Patients
- Study of Efficacy and Safety of LIB003 in Patient With CVD on Statins Requiring Additional LDL-C Red…
- Study of Long-Term Efficacy and Safety of LIB003 in CVD or High Risk for CVD Patients Needing Furthe…
