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MELK
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Summary
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Body Atlas
Most Correlated Tissues
Granulocyte-macrophage progenitor cell of bone marrow
Hematopoietic stem cell of bone marrow
Plasma cell of spleen
Thymus gland
Bone marrow
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Disease Atlas
Most Correlated Diseases
Epstein-Barr virus disease
Retinoblastoma
Sepsis due to Gram negative bacteria
Bacterial septicemia
Injury of lung
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Pharmaco Atlas
Most Correlated Compounds
epothilone B
bromohydrin pyrophosphate
NU 7026
ischemin
Epstein-Barr Virus Nuclear Antigens
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Knockdown Atlas
Most Correlated Gene Perturbations
OTUD1
HIST1H1B
H1F0
GNAS
KRIT1
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Curated Studies
Most Correlated Studies
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Literature
Most Relevant Literature
The crystal structure of MPK38 in complex with OTSSP167, an orally administrative MELK selective inh…
MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in prolif…
Ablation of AMPK-Related Kinase MPK38/MELK Leads to Male-Specific Obesity in Aged Mature Adult Mice.
MELK/MPK38 in cancer: from mechanistic aspects to therapeutic strategies.
DAXX ameliorates metabolic dysfunction in mice with diet-induced obesity by activating the AMP-activ…
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Clinical Trials
Most Relevant Clinical Trials
Safety Study of MELK Inhibitor to Treat Patients With Advanced Breast Cancer and Triple Negative Bre…
Treatment of Insufficient Superficial and Perforatring Veins of the Lower Limb Using HIFU
Treatment of Insufficient Superficial and Perforating Veins of the Lower Limb Using HIFU
Phase 1 Study of OTS167 in Patients With Solid Tumors
Pharmacological Study of Intravenous OTS167 in Patients With Refractory or Relapsed Acute Myeloid Le…
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