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QuickView for MG-132 (compound)


Genetic Markers

Most Correlated Genes

  1. HMOX1
  2. SLC7A11
  3. GADD45A
  4. ATF3
  5. HSPA1A
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Pathway Enrichment

Most Correlated Biogroups

  1. BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP
  2. BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN
  3. GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP
  4. organic cyclic compound metabolic process
  5. heterocycle metabolic process
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Curated Studies

Most Correlated Studies

No studies found
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Literature

Most Relevant Literature

  1. Inhibition of rat liver cathepsins B and L by the peptide aldehyde benzyloxycarbonyl-leucyl-leucyl-l…
  2. Centrosomal aggregates and Golgi fragmentation disrupt vesicular trafficking of DAT.
  3. c-Myc down-regulation is involved in proteasome inhibitor-mediated enhancement of radiot…
  4. MG132, a proteasome inhibitor, induces apoptosis in tumor cells.
  5. Combination of quercetin and tannic acid in inhibiting 26S proteasome affects S5a and 20S expression…
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Clinical Trials

Most Relevant Clinical Trials

  1. Dose Escalation Study of the Pharmacodynamics, Pharmacokinetics, Safety, and Immunogenicity of BCD-1…
  2. Comparative Study of the Efficacy and Safety of BCD-132 With Teriflunomide and Placebo in Multiple S…
  3. A Phase 2a of RSLV-132 in Subjects With Systemic Lupus Erythematosus (SLE)
  4. Phase 2 Study of RSLV-132 in Subjects With Long COVID
  5. A Study of RSLV-132 in Subjects With Primary Sjogren's Syndrome
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