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MK‑2206
Summary
General Info
Curated Studies
Most Correlated Studies
Non-small cell lung cancer NCI-H1666 cells infected with Influenza A(H1N1) and treated with MK2206
Breast cancer cell lines and xenografts treated with PI3KA or AKT inhibitors
Prostate cancer mouse models treated with different compounds
Breast duct carcinoma T-47D cells treated with AKT inhibitor MK2206
Multiple cancer cell lines treated with 32 kinase inhibitors
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Literature
Most Relevant Literature
A phase 2 study of MK-2206 in patients with incurable adenoid cystic carcinoma (Alliance A091104).
MK2206 attenuates atherosclerosis by inhibiting lipid accumulation, cell migration, proliferation, a…
The Synergistic Inhibitory Effect of Combining MK-2206 and AZD 6244 in MARIMO Cells Harboring a Calr…
Combined treatment with ruxolitinib and MK-2206 inhibits the JAK2/STAT5 and PI3K/AKT pathways via ap…
Co-Administration of Anticancer Candidate MK-2206 Enhances the Efficacy of BCG Vaccine Against Mycob…
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Clinical Trials
Most Relevant Clinical Trials
A Study of MK-2206 in Combination With Trastuzumab and Lapatinib for the Treatment of HER2+ Solid Tu…
A Phase I Study of MK-2206 in Combination With Standard Chemotherapy in Participants With Locally Ad…
Dose Escalation Study With MK-2206 in Patients With Locally Advanced or Metastatic Solid Tumors (MK-…
Safety and Tolerability of Different Dose Combinations of Ridaforolimus With MK-2206 or MK-0752 for …
Study of MK 2206 in Patients With Relapsed or Refractory Diffuse Large B Cell Lymphoma
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