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QuickView for MK-801 (compound)


Genetic Markers

Most Correlated Genes

  1. EGR2
  2. FOS
  3. CYR61
  4. EFCAB1
  5. SLC24A1
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Pathway Enrichment

Most Correlated Biogroups

  1. UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
  2. NAGASHIMA_EGF_SIGNALING_UP
  3. GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_UP
  4. GSE37605_TREG_VS_TCONV_NOD_FOXP3_FUSION_GFP_UP
  5. CHASSOT_SKIN_WOUND
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Curated Studies

Most Correlated Studies

  1. Prefrontal cortex of male SD rats treated with NMDAR antagonist MK-801 to induce schizophrenia
  2. Transcriptome of MK-801 treated Rat Brain
  3. Cortical neurons exposed to excitotoxic NMDA and potentially neuroprotective compounds
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Literature

Most Relevant Literature

  1. Characteristics of MK-801-induced locomotor sensitization.
  2. Neuroprotective effects of MK-801 against cerebral ischemia reperfusion.
  3. Acute MK-801 increases measures of both sign-tracking and goal-tracking in male Sprague-Dawley rats.
  4. Focused Ultrasound Stimulates the Prefrontal Cortex and Prevents MK-801-Induced Psychiatric Symptoms…
  5. Effect of intermittent subchronic MK-801 administration on dopamine synthesis capacity and responsiv…
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Clinical Trials

Most Relevant Clinical Trials

  1. Study of MK-4830 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With…
  2. Efficacy and Safety of MK-1942 When Added to Stable Antidepressant Therapy in Participants With Trea…
  3. Efficacy and Safety of MK-1942 as an Adjunct Therapy in Participants With Mild to Moderate Alzheimer…
  4. MK-1942/Donepezil Interactions in Participants With Alzheimer's Disease (MK-1942-005)
  5. Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currentl…
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