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Motor neuron disease
(phenotype)
Summary
General Info
Genetic Markers
Most Correlated Genes
Most Correlated SNPs
DCTN1
ANXA11
AR
SMAR
SPART
No SNPs found
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Pathway Enrichment
Most Correlated Biogroups
regulation of nitrogen compound metabolic process
NUYTTEN_EZH2_TARGETS_UP
PILON_KLF1_TARGETS_DN
cytosol
CUI_TCF21_TARGETS_2_DN
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Curated Studies
Most Correlated Studies
Spinal cord, blood and muscle from 70d and 100d old from an ALS mouse model (G93A-SOD1)
Oculomotor and lumbar spinal motor neurons in amyotrophic lateral sclerosis (ALS) susceptibility
Motor neurons vulnerable to amyotrophic lateral sclerosis (ALS).
Spinal motor neurons from SOD1 mice (ALS disease model) at 15wk - G-CSF or placebo treated
Motor neurons derived from iPSCs of C9ORF72 carriers with Amyotrophic lateral sclerosis
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Literature
Most Relevant Literature
Promises and pitfalls of imaging-based biomarkers in motor neuron diseases.
Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases.
Prevalence of motor neuron diseases in gout patients: a nationwide population-based cohort study.
Muscle MRI in motor neuron diseases: a systematic review.
Temporal course of cognitive and behavioural changes in motor neuron diseases.
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Clinical Trials
Most Relevant Clinical Trials
Serial Fasciculation Measurements in Motor Neurone Disease
Levetiracetam for Cramps, Spasticity and Neuroprotection in Motor Neuron Disease
A Study of Monepantel in Individuals With Motor Neurone Disease
EncoreAnywhere Use in Motor Neurone Disease
Oxidative Stress in Motor Neuron Disease: COSMOS Add-On Study
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