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N-ethyl-N-nitrosourea
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NextBio Summary
General Info
Genetic Markers
Most Correlated Genes
PDE4C
REN
CSTA
Ren2
ACOT1
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Pathway Enrichment
Most Correlated Biogroups
mitochondrion
cytosol
nucleoplasm
response to stress
regulation of nitrogen compound metabolic process
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Curated Studies
Most Correlated Studies
Liver gene expression regulated by Dicer1 in mice treated with ENU
HepG2 cells treated with genotoxic and non-genotoxic agents
Splenic gene expression in AML mice expressing full length and truncated CBFb-SMMHC fusion protein
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Literature
Most Relevant Literature
Induction of Liver Tumors in Mice with N-Ethyl-N-Nitrosourea or N-Nitrosodiethylamine.
Tissue-specific and time-dependent clonal expansion of ENU-induced mutant cells in gpt delta mice.
Single-cell transcriptogenomics reveals transcriptional exclusion of ENU-mutated alleles.
N-Ethyl-N-Nitrosourea (ENU) Mutagenesis Reveals an Intronic Residue Critical for Caenorhabditis eleg…
Braf Mutations Initiate the Development of Rat Gliomas Induced by Postnatal Exposure to N-Ethyl-N-Ni…
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Clinical Trials
Most Relevant Clinical Trials
FOLFOX Followed by FOLFIRI or Reverse Sequence Treatment in Advanced Gastric Cancer (AGC)
Everolimus, Letrozole and Trastuzumab in HR- and HER2/Neu-positive Patients
A Study Evaluating the Safety, Tolerability of LPM3480226 Tablets in Patients With Advanced Solid Tu…
A Phase II Study of BAY 43-9006 (Sorafenib) in Metastatic, Androgen-Independent Prostate Cancer
MK-2206 and AZD6244 in Patients With Advanced Colorectal Carcinoma
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