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QuickView for N-ethyl-N-nitrosourea (compound)


Genetic Markers

Most Correlated Genes

  1. PDE4C
  2. REN
  3. CSTA
  4. Ren2
  5. ACOT1
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Pathway Enrichment

Most Correlated Biogroups

  1. mitochondrion
  2. cytosol
  3. nucleoplasm
  4. response to stress
  5. regulation of nitrogen compound metabolic process
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Curated Studies

Most Correlated Studies

  1. Liver gene expression regulated by Dicer1 in mice treated with ENU
  2. HepG2 cells treated with genotoxic and non-genotoxic agents
  3. Splenic gene expression in AML mice expressing full length and truncated CBFb-SMMHC fusion protein
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Literature

Most Relevant Literature

  1. Induction of Liver Tumors in Mice with N-Ethyl-N-Nitrosourea or N-Nitrosodiethylamine.
  2. Tissue-specific and time-dependent clonal expansion of ENU-induced mutant cells in gpt delta mice.
  3. Single-cell transcriptogenomics reveals transcriptional exclusion of ENU-mutated alleles.
  4. N-Ethyl-N-Nitrosourea (ENU) Mutagenesis Reveals an Intronic Residue Critical for Caenorhabditis eleg…
  5. Braf Mutations Initiate the Development of Rat Gliomas Induced by Postnatal Exposure to N-Ethyl-N-Ni…
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Clinical Trials

Most Relevant Clinical Trials

  1. FOLFOX Followed by FOLFIRI or Reverse Sequence Treatment in Advanced Gastric Cancer (AGC)
  2. Everolimus, Letrozole and Trastuzumab in HR- and HER2/Neu-positive Patients
  3. A Study Evaluating the Safety, Tolerability of LPM3480226 Tablets in Patients With Advanced Solid Tu…
  4. A Phase II Study of BAY 43-9006 (Sorafenib) in Metastatic, Androgen-Independent Prostate Cancer
  5. MK-2206 and AZD6244 in Patients With Advanced Colorectal Carcinoma
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