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NAE1
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Body Atlas
Most Correlated Tissues
Granulocyte-macrophage progenitor cell of bone marrow
T Lymphocyte (regulatory) of peripheral blood
Hematopoietic stem cell of bone marrow
Parotid gland
B lymphocyte (naive) of spleen
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Neddylation is critical to cortical development by regulating Wnt/β-catenin signaling.
Bi-allelic variants in NAE1 cause intellectual disability, ischiopubic hypoplasia, stress-mediated l…
HPP1 Ectodomain Shedding is Mediated by ADAM17 and is Necessary for Tumor Suppression in Colon Cance…
Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumor…
Dissecting Distinct Roles of NEDDylation E1 Ligase Heterodimer APPBP1 and UBA3 Reveals Potential Evo…
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Testing the Combination of Pevonedistat With Chemotherapy for Bile Duct Cancer of the Liver
Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Adva…
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