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NVP-BEZ235
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
TXNIP
FAXDC2
NPR3
RBP4
AGR2
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Pathway Enrichment
Most Correlated Biogroups
cytosol
organic cyclic compound binding
heterocyclic compound binding
regulation of nitrogen compound metabolic process
PUJANA_BRCA1_PCC_NETWORK
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Curated Studies
Most Correlated Studies
Effect of NVP-BEZ235 on growth of ovarian cancer cell lines
Comparison of gene expression alterations induced by distinct PI3K inhibitors
Lung cancer HCC827 EGFR-mutant cells following treatment with targeted therapies
Melanoma Me13 cells treated with MEK1/2, PI3K/mTOR, mTOR, and BRAF V600E inhibitors
Hepatocellular carcinomas treated with PI3K/mTOR inhibitors
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Literature
Most Relevant Literature
The synergistic antitumor effect of IL-6 neutralization with NVP-BEZ235 in hepatocellular carcinoma.
NVP-BEZ235 or JAKi Treatment leads to decreased survival of examined GBM and BBC cells.
The phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 is effective in inh…
NVP-BEZ235 Inhibits Renal Cell Carcinoma by Targeting TAK1 and PI3K/Akt/mTOR Pathways.
Identification and panoramic analysis of drug response-related genes in triple negative breast cance…
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Clinical Trials
Most Relevant Clinical Trials
Evaluation Of The Treatment Effectiveness Of Glioblastoma / Gliosarcoma Through The Suppression Of T…
Lapatinib and RAD-001 for HER2 Positive Metastatic Breast Cancer
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