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QuickView for Na+ channel (gene)


Body Atlas

Most Correlated Tissues

  1. Parietal lobe
  2. Cerebral cortex
  3. Frontal lobe
  4. Hippocampus
  5. Thalamus lateral nuclei
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Disease Atlas

Most Correlated Diseases

  1. Cerebellar ataxia
  2. Developmental mental disorder
  3. Alzheimer's disease
  4. Dementia
  5. Huntington's disease
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Pharmaco Atlas

Most Correlated Compounds

  1. 4-hydroxyestradiol-17 beta
  2. 2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline
  3. Ampyrone
  4. N-Methyl-3,4-methylenedioxyamphetamine
  5. methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. MIR211
  2. TMPRSS11B
  3. MBNL1
  4. EN2
  5. ENPP2
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syn…
  2. Mutations in the Scn8a DIIS4 voltage sensor reveal new distinctions among hypomorphic and null Nav 1…
  3. Gabra2 is a genetic modifier of Scn8a encephalopathy in the mouse.
  4. Regulation of Thalamic and Cortical Network Synchrony by Scn8a.
  5. Altered gene expression profile in a mouse model of SCN8A encephalopathy.
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Clinical Trials

Most Relevant Clinical Trials

  1. Na+ Channel mRNA Regulation in Heart Failure
  2. Regulation of KATP Channels and Na+/K+ ATPase in Relation to Fatigue Development
  3. Sodium Channel Splicing in Heart Failure Trial
  4. Sodium Channel Splicing in Heart Failure Trial (SOCS-HEFT) Prospective Study
  5. Expanded Access Use of Stiripentol in Dravet Syndrome or Sodium Channel Mutation Epileptic Encephalo…
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