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(e.g. CYP51, Metabolism of xenobiotics, Leukemia, Liver, Neocentromeres, Trichostatin A)
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QuickView for Npc1 (gene)


Body Atlas

Most Correlated Tissues

  1. Adrenal gland cortex
  2. Microglial cell
  3. Corpus callosum
  4. Parotid gland
  5. Nodose nucleus
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Disease Atlas

Most Correlated Diseases

  1. Sphingomyelin/cholesterol lipidosis
  2. Injury of eye region
  3. Lyme disease
  4. Cardiomegaly
  5. Caseating tuberculoid granuloma
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Pharmaco Atlas

Most Correlated Compounds

  1. Propoxycaine
  2. Ampicillin
  3. Histone Deacetylase Inhibitors
  4. ACVR2B protein, human
  5. tetrandrine
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. CHMP2A
  2. NPC1
  3. GADD45B
  4. CRYAB
  5. COL10A1
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. NPC1 is required for postnatal islet β cell differentiation by maintaining mitochondria turnover.
  2. An overview of the role of Niemann-pick C1 (NPC1) in viral infections and inhibition of viral infect…
  3. Npc1 gene mutation abnormally activates the classical Wnt signalling pathway in mouse kidneys and pr…
  4. Tubeimosides are pan-coronavirus and filovirus inhibitors that can block their fusion protein bindin…
  5. In silico comparative analysis of cestode and human NPC1 provides insights for ezetimibe repurposing…
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Clinical Trials

Most Relevant Clinical Trials

  1. VTS-270 to Treat Niemann-Pick Type C1 (NPC1) Disease
  2. Study of the Pharmacokinetics of Trappsol and Effects on Potential Biomarkers of Niemann-Pick C1 (NP…
  3. Adrabetadex to Treat Niemann-Pick Type C1 (NPC1) Disease
  4. Biomarker for Niemann Pick Type C Disease (BioNPC)
  5. Phase 1/2 Study of Vorinostat Therapy in Niemann-Pick Disease, Type C1
Explore Clinical Trials Results
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