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QuickView for Npr1 (gene)


Body Atlas

Most Correlated Tissues

  1. Ciliary ganglion
  2. Atrioventricular node
  3. Skeletal muscle psoas
  4. Cerebellum peduncles
  5. Pons
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Disease Atlas

Most Correlated Diseases

  1. Placental insufficiency
  2. Poisoning by drug AND/OR medicinal substance
  3. 11p partial monosomy syndrome
  4. Toxic nephropathy
  5. Kidney transplant failure and rejection
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Pharmaco Atlas

Most Correlated Compounds

  1. isosorbide-5-mononitrate
  2. Isosorbide Dinitrate
  3. Nitroglycerin
  4. Nitroprusside
  5. Nitric Oxide
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. KMT2B
  2. BAG3
  3. PTHLH
  4. LEPR
  5. RPS2
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. NPRA promotes fatty acid metabolism and proliferation of gastric cancer cells by binding to PPARĪ±.
  2. MSC-NPRA loop drives fatty acid oxidation to promote stemness and chemoresistance of gastric cancer.
  3. Natriuretic peptide receptor a promotes gastric malignancy through angiogenesis process.
  4. Ligand-Dependent Downregulation of Guanylyl Cyclase/Natriuretic Peptide Receptor-A: Role of miR-128 …
  5. Deletion of AT1a receptors selectively in the proximal tubules alters the hypotensive and natriureti…
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Clinical Trials

Most Relevant Clinical Trials

  1. Study to Assess the Safety, Tolerability, and Pharmacokinetics of REGN5381 (an NPR1 Agonist) in Adul…
  2. Study of Natriuretic Peptide Receptor 1 (NPR1) Antagonist in Adult Patients With Postural Orthostati…
  3. A Study of REGN7544 for the Treatment in Adult Patients With Sepsis-Induced Hypotension
  4. REGN5381 in Adult Participants With Uncontrolled Hypertension
  5. A Trial to Learn if Different Doses of REGN7544 Are Safe in Healthy Adult Participants
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