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Nse2
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Summary
General Info
Body Atlas
Most Correlated Tissues
No tissues found
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Disease Atlas
Most Correlated Diseases
No diseases found
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Pharmaco Atlas
Most Correlated Compounds
No compounds found
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Knockdown Atlas
Most Correlated Gene Perturbations
isp7
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Curated Studies
Most Correlated Studies
S. pombe with mutations in MYST and GNAT family acyl transferases
Transcriptional response of S. cerevisiae to change in oxygen provision
S. pombe wildtype or red2 deletion strains
S. pombe overexpressing RPL32-1 or RPL32-2 grown to log and stationary phases.
S. pombe of wildtype or pap1-deleted strains treated with DETANONOate
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Literature
Most Relevant Literature
SUMO-targeted ubiquitin ligase, Rad60, and Nse2 SUMO ligase suppress spontaneous Top1-mediated DNA d…
SUMO ligase activity of vertebrate Mms21/Nse2 is required for efficient DNA repair but not for Smc5/…
The Nse2/Mms21 SUMO ligase of the Smc5/6 complex in the maintenance of genome stability.
Nse1, Nse2, and a novel subunit of the Smc5-Smc6 complex, Nse3, play a crucial role in meiosis.
Nse2, a component of the Smc5-6 complex, is a SUMO ligase required for the response to DNA damage.
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Clinical Trials
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There were no clinical trials for Nse2
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