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QuickView for Otx2 (gene)


Body Atlas

Most Correlated Tissues

  1. Thalamus
  2. Thalamus lateral nuclei
  3. Ventral tegmental area
  4. Cerebellum
  5. Subthalamic nucleus
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Disease Atlas

Most Correlated Diseases

  1. Dysostosis
  2. Chronic sinusitis
  3. Microphthalmos
  4. Neuroendocrine tumor
  5. Brain cancer
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Pharmaco Atlas

Most Correlated Compounds

  1. SHH protein, human
  2. NOG protein, human
  3. Methamphetamine
  4. 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide
  5. Macrocyclic Compounds
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. CCNB1
  2. TFCP2L1
  3. SMARCC2
  4. RPS2
  5. HELZ
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. c-Jun N-terminal kinase 1 (JNK1) phosphorylates OTX2 transcription factor that regulates early retin…
  2. OTX2 duplications: a recurrent cause of oculo-auriculo-vertebral spectrum.
  3. Photoreceptor cKO of OTX2 Enhances OTX2 Intercellular Transfer in the Retina and Causes Photophobia.
  4. OTX2 mutation associated with severe myopia in a Canadian family.
  5. Novel OTX2 loss of function variant associated with congenital hypopituitarism without eye abnormali…
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Clinical Trials

Most Relevant Clinical Trials

  1. Imipenem/Relebactam/Cilastatin Versus Piperacillin/Tazobactam for Treatment of Participants With Bac…
  2. Incidence of cCPHD in Denmark - a National Observational Study
  3. Survival of Monocytes Collected From Patients With Atrophic AMD in Retinal Pigmented Epithelium Expl…
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