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QuickView for PD0325901 (compound)


Genetic Markers

Most Correlated Genes

  1. SERPINA3
  2. CRIP1
  3. RBP4
  4. DUSP6
  5. XIST
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Pathway Enrichment

Most Correlated Biogroups

  1. regulation of nitrogen compound metabolic process
  2. organic cyclic compound binding
  3. heterocyclic compound binding
  4. organic cyclic compound metabolic process
  5. cell differentiation
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Curated Studies

Most Correlated Studies

  1. Investigations on the role of Blimp1 in pluripotency and reprogramming
  2. iPSC gene expression in response to culture with a small molecule inhibitor cocktail
  3. Tracing the conversion process for primordial germ cells to pluripotent stem cells
  4. Apollon knockdown in a melanoma cell line treated with fotemustine, PLX4720 or PD0325901
  5. Rapamycin and PD0325901 treatment in a metastatic prostate cancer model
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Literature

Most Relevant Literature

  1. PD0325901, an ERK inhibitor, attenuates RANKL-induced osteoclast formation and mitigates cartilage i…
  2. MEK inhibitor PD0325901 significantly boosts ssODN-mediated HDR efficiency in porcine fetal fibrobla…
  3. Inhibition of glioblastoma dispersal by the MEK inhibitor PD0325901.
  4. Modulation of spine fusion with BMP-2, MEK inhibitor (PD0325901), and zoledronic acid in a murine mo…
  5. NF106: A Neurofibromatosis Clinical Trials Consortium Phase II Trial of the MEK Inhibitor Mirdametin…
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Clinical Trials

Most Relevant Clinical Trials

  1. MEK Inhibitor PD-325901 To Treat Advanced Non-Small Cell Lung Cancer
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