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PD0332991
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
KIF20A
XIST
CRIP1
RRM2
CCNA2
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Pathway Enrichment
Most Correlated Biogroups
FISCHER_DREAM_TARGETS
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP
nucleoplasm
PUJANA_BRCA1_PCC_NETWORK
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP
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Curated Studies
Most Correlated Studies
T-ALL cell line KOPTK1 treated with CDK4/6 inhibitor PD 0332991
Breast cancer V720 cells treated with CDK4/6 inhibitor PD 0332991
Pancreatic ductal adenocarcinoma AsPC-1 and COLO-357 cells treated with CDK4 6 inhibitor PD 0332991
Breast cancer ER+ T47D cells treated with palbociclib to develop drug resistance
Breast carcinoma T-47D cells resistant or ex-resistant to palbociclib
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Literature
Most Relevant Literature
Palbociclib (PD 0332991) Interaction with Kinases. Theoretical and Comparative Molecular Docking Stu…
Applications and mechanisms of the cyclin-dependent kinase 4/6 inhibitor, PD-0332991, in solid tumor…
FAM117A Is a New Prognostic Marker of Lung Adenocarcinoma and Predicts Sensitivity to PD0332991.
Expression of CDK6 in Stomach Cancer and the Effect of CDK4/6 Inhibitor PD-0332991 on the Function o…
PD-0332991 combined with cisplatin inhibits nonsmall cell lung cancer and reversal of cisplatin resi…
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Clinical Trials
Most Relevant Clinical Trials
Cyclin Dependent Kinase (CDK)4/6 Inhibitor, PD0332991 in Advanced Non-small Cell Lung Cancer NSCLC.
A Open Label Study of the Efficacy and Safety of PD0332991 a Selective Inhibitor of the Cyclin Depen…
PD0332991 (Palbociclib) in Patients With Advanced or Metastatic Liposarcoma
Safety and Efficacy of PD0332991 (Palbociclib), a Cyclin-dependent Kinase 4 and 6 Inhibitor, in Pati…
PD0332991/Paclitaxel in Advanced Breast Cancer
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