QuickView for PDE12 (gene)

1. The Role of Phosphodiesterase 12 (PDE12) as a Negative Regulator of the Innate Immune Response and t…
2. Inhibition of phosphodiesterase 12 results in antiviral activity against several RNA viruses includi…
3. Maturation of selected human mitochondrial tRNAs requires deadenylation.
4. PDE12 removes mitochondrial RNA poly(A) tails and controls translation in human mitochondria.
5. Elongational stalling activates mitoribosome-associated quality control.

There were no clinical trials for PDE12