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PDE4 inhibitor
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Curated Studies
Most Correlated Studies
Bronchus epithelial BEAS-2B cells with temporal treatment of GS-5759 or indacaterol and GSK256066
Rolipram treated B-CLL, normal B, and normal T cells
Atopic dermatitis lesional skin tissues from patients treated with Crisaborole (AN2728) ointment
Intracranial xenografts of glioblastoma patient-derived cancer stem cells with DPY30 knockdown
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Literature
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PDE4 inhibitors for disease therapy: advances and future perspective.
PDE4 Inhibitors: Profiling Hits through the Multitude of Structural Classes.
Pharmacology of orismilast, a potent and selective PDE4 inhibitor.
Development of an amorphous based sustained release system for apremilast a selective phosphodiester…
Pharmacology, clinical efficacy, and tolerability of phosphodiesterase-4 inhibitors: impact of human…
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Clinical Trials
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A 24-wk Dose Ranging Study to Evaluate the Efficacy and Safety of 4 Doses of a New PDE4 Inhibitor in…
Pilot Study Evaluating the Efficacy of a Topical PDE4 Inhibitor for Morphea
A Proof-of-principle Study of Oral Treatment of Non-alcoholic Steatohepatitis With a Novel PDE4 Inhi…
Healthy Volunteer Positron Emission Tomography (PET) Brain Occupancy Study of a Phosphodiesterase 4 …
Antidepressant Effects on cAMP Specific Phosphodiesterase (PDE4) in Depressed Patients
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