QuickView for PHLPP (gene)

1. H3K4me3 ChIP-chip analysis in Drosophila Oregon-R strain 2-4 hour embryos (modENCODE)
2. MRG15 occupancy in Drosophila larval CNS-derived cell line ML-DmBG3-c2 by ChIP-chip (modENCODE)
3. MRG15 occupancy in Drosophila embryonic cell line Kc167 by ChIP-chip (modENCODE)
4. H2AV ChIP analysis of 2-4 hour Drosophila embryos (modENCODE)
5. Epigenetically heritable alteration of fly development in response to toxic challenge

1. Discovery of small molecule inhibitors of the PH domain leucine-rich repeat protein phosphatase (PHL…
2. Increased levels of the Akt-specific phosphatase PH domain leucine-rich repeat protein phosphatase (…
3. miR-190-mediated downregulation of PHLPP contributes to arsenic-induced Akt activation and carcinoge…
4. Cutting edge: PHLPP regulates the development, function, and molecular signaling pathways of regulat…
5. PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor gr…

There were no clinical trials for PHLPP