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PI-103
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Summary
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Genetic Markers
Most Correlated Genes
XIST
RBP4
CPVL
CRIP1
MAL
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Pathway Enrichment
Most Correlated Biogroups
cytosol
regulation of nitrogen compound metabolic process
organic cyclic compound binding
heterocyclic compound binding
organic cyclic compound metabolic process
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Curated Studies
Most Correlated Studies
SY5Y cells overexpressing FOXO3A treated with PI-103
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Hepatocellular carcinoma HEPG2 cells treated with small molecule perturbagens
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
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Literature
Most Relevant Literature
RIDR-PI-103, ROS-activated prodrug PI3K inhibitor inhibits cell growth and impairs the PI3K/Akt path…
Development of a bioavailable boron-containing PI-103 Bioisostere, PI-103BE.
Two-pore channel blockade by phosphoinositide kinase inhibitors YM201636 and PI-103 determined by a …
Opposite effects of the triple target (DNA-PK/PI3K/mTOR) inhibitor PI-103 on the radiation sensitivi…
Synergistic Anticancer Strategy of Sonodynamic Therapy Combined with PI-103 Against Hepatocellular C…
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Clinical Trials
Most Relevant Clinical Trials
A Study of CST-103 Co-administered With CST-107 in Subjects With Neurodegenerative Disorders
Evaluation of the Attenuation by Aes-103 of Hypoxia Mediated Decrements in Endurance Exercise Perfor…
Safety, Pharmacokinetics, and Pharmacodynamics/Efficacy of SBC-103 in Mucopolysaccharidosis III, Typ…
A Study to Evaluate the Efficacy and Safety of DR-103 for the Prevention of Pregnancy
A Study of CST-103 Co-administered With CST-107 in Subjects With Parkinson's Disease Having Freezing…
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