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QuickView for PKAN (gene)


Body Atlas

Most Correlated Tissues

  1. Macrophage of peripheral blood
  2. Myeloid cells of peripheral blood
  3. Basophil of peripheral blood
  4. Natural killer cell of peripheral blood
  5. Monocyte of peripheral blood
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Disease Atlas

Most Correlated Diseases

  1. Disorder of intraocular pressure
  2. Multiple-resistant Staphylococcus aureus infection
  3. Caseating tuberculoid granuloma
  4. Aspergillosis
  5. Muscle cachexia
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Pharmaco Atlas

Most Correlated Compounds

  1. isonicotinamide
  2. Sodium Iodide
  3. 4'-deaza-1'-aza-2'-deoxy-1'-(9-methylene)-immucillin A
  4. propylene glycol mono-t-butyl ether
  5. Tannins
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. GSDME
  2. NR4A3
  3. PRKG1
  4. FOSL2
  5. IGH
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. PKAN pathogenesis and treatment.
  2. PANK2 p.A170fs：a novel pathogenetic mutation, compound with PANK2 p.R440P, causing pantothenate kina…
  3. Redesigning therapies for pantothenate kinase-associated neurodegeneration.
  4. A Potential Citrate Shunt in Erythrocytes of PKAN Patients Caused by Mutations in Pantothenate Kinas…
  5. Therapeutic approach with commercial supplements for pantothenate kinase-associated neurodegeneratio…
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Clinical Trials

Most Relevant Clinical Trials

  1. Brain Perfusion in Pantothenate Kinase-associated Neurodegeneration (PKAN)
  2. Efficacy and Safety Study of Fosmetpantotenate (RE-024) in PKAN Participants
  3. Compassionate Use of Deferiprone in Patients With PKAN
  4. Efficacy and Safety Study of Deferiprone in Patients With Pantothenate Kinase-associated Neurodegene…
  5. CoA-Z in Pantothenate Kinase-associated Neurodegeneration (PKAN)
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