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QuickView for Perfluorooctanoic acid (compound)


Genetic Markers

Most Correlated Genes

  1. Acot1
  2. PLIN2
  3. CYP4A11
  4. ACOT2
  5. EHHADH
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Pathway Enrichment

Most Correlated Biogroups

  1. lipid metabolic process
  2. cytosol
  3. HALLMARK_FATTY_ACID_METABOLISM
  4. mitochondrion
  5. organic cyclic compound binding
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Curated Studies

Most Correlated Studies

  1. Hepatocytes isolated from rats and treated with 29 ToxCast chemicals in a dose-dependent manner
  2. Livers from wildtype and Ppara knockout mice treated with perfluorooctanoic acid
  3. Lung and liver of mouse fetuses exposed to perfluorooctanoic acid
  4. Livers of Wild-Type and PPARalpha-Null Mice Exposed to Perfluorooctanoic Acid (PFOA)
  5. Transcriptional Effects Upon Perfluoroalkyl Acid Exposure
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Literature

Most Relevant Literature

  1. Perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) in surface waters, sediments, …
  2. Mode of Action analysis of perfluorooctanoic acid (PFOA) tumorigenicity and Human Relevance.
  3. Dose-dependent reactions of Aporrectodea caliginosa to perfluorooctanoic acid and perfluorooctanesul…
  4. Can nail, hair and urine be used for biomonitoring of human exposure to perfluorooctane sulfonate an…
  5. Cellular response of freshwater green algae to perfluorooctanoic acid toxicity.
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Clinical Trials

Most Relevant Clinical Trials

  1. Clinical Tests to Predict the Success of Assisted Reproductive Techniques
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