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Polyglutamine
(compound)
Summary
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Genetic Markers
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Curated Studies
Most Correlated Studies
Polyglutamine expansion mutations of huntintin in yeast deletion strains - bna4, mbf1, ume1
Drosophila gene expression during aging regulated by ubiquitous expression of polyglutamine Atrophin
Heads from WT and Tim-gal4 polyglutamine-expanded neurotoxic protein (MJDtr78Q; MJD) mutant flies
Quadriceps muscle transcriptional profile in spinal bulbar muscular atrophy mouse model
Cerebellum and forbrain from ataxin-1 mutant mice
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Literature
Most Relevant Literature
Autophagy preferentially degrades non-fibrillar polyQ aggregates.
Predicting the involvement of polyQ- and polyA in protein-protein interactions by their amino acid c…
Expanded polyQ aggregates interact with sarco-endoplasmic reticulum calcium ATPase and Drosophila in…
Disrupted nuclear import of cell cycle proteins in Huntington's/PolyQ disease causes neurodevelopmen…
Binding structures of SERF1a with NT17-polyQ peptides of huntingtin exon 1 revealed by SEC-SWAXS, NM…
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Clinical Trials
Most Relevant Clinical Trials
Efficacy and Safety Study of Stemchymal® in Polyglutamine Spinocerebellar Ataxia
Pilot Study of Safety and Efficacy of Sodium Phenylbutyrate in Spinocerebellar Ataxia Type 3
Integrated Functional Evaluation of the Cerebellum
Efficacy Of Oral Trehalose In Spinocerebellar Ataxia 3
Genetic Polymorphism of the Androgen Receptor-Gene and Sexual Function in Middle Aged Women
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