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Most Correlated Studies
- Melanoma with WT and mutant B-RAF and N-RAS
- Midgut expression profiles in RAF and NOTCH transgenic Drosophila
- Cutaneous squammous cell carcinoma B9 cells with HRAS-Q61L treated with RAF inhibitors
- Lung dysplasia induced by c-Raf and associated gene expression profiles in transgenic mice
- Lung cancer induced by c-Raf and associated gene expression profiles in transgenic mice
Most Relevant Literature
- Analysis of the ERK Pathway Cysteinome for Targeted Covalent Inhibition of RAF and MEK Kinases.
- Design and synthesis of 4-anilinoquinazolines as Raf kinase inhibitors. Part 1. Selective B-Raf/B-Ra…
- Inhibition of RAF dimers: it takes two to tango.
- On the development of B-Raf inhibitors acting through innovative mechanisms.
- Therapeutic implications of B-RAF mutations in colorectal cancer.
Most Relevant Clinical Trials
- Evaluation of Pathway Modulation by Raf, MEK, & Kinase Inhibitors
- Assessment of the V600E Mutation in the B-RAF Gene in Chronic Lymphoproliferative Disease
- Trial of Dasatinib in Patients With Advanced Cancers Harboring DDR2 Mutation or Inactivating B-RAF M…
- MEK162 for Patients With RAS/RAF/MEK Activated Tumors
- Interest of the 18F-DOPA-PET Imaging in Metastatic Melanoma Treated With B-RAF Inhibitors: a Pilot S…
