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RB protein
(compound)
Summary
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Genetic Markers
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Pathway Enrichment
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Curated Studies
Most Correlated Studies
Role of retinoblastoma protein (Rb) in mouse Sertoli cells function
Rb gene family during embryonic development
Placenta of RB-E2f4 double or Rb KO in female mice at E13.5 and E11.5 respectively
Breast adenocarcinoma MCF-7 cells depleted of RB and treated with anti-IL6 antibody
Prostate adenocarcinoma LNCaP cells with RB shRNA and cultured in CDT media
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Literature
Most Relevant Literature
PP2A/B55α substrate recruitment as defined by the retinoblastoma-related protein p107.
Retinoblastoma protein controls growth, survival and neuronal migration in human cerebral organoids.
Structural basis for tunable affinity and specificity of LxCxE-dependent protein interactions with t…
Retinoblastoma Protein Knockdown Favors Oxidative Metabolism and Glucose and Fatty Acid Disposal in …
Multiple mechanisms for E2F binding inhibition by phosphorylation of the retinoblastoma protein C-te…
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Clinical Trials
Most Relevant Clinical Trials
Safety and Efficacy of PD0332991 (Palbociclib), a Cyclin-dependent Kinase 4 and 6 Inhibitor, in Pati…
[18F]FLT PET/CT in Rb+ Metastatic Breast Cancer
Alisertib and Pembrolizumab for the Treatment of Patients With Rb-deficient Head and Neck Squamous C…
A Trial of Ribocilcib (LEE011) and Weekly Paclitaxel in Patients With Rb+ Advanced Breast Cancer
A Phase II Study of Androgen Deprivation Therapy With or Without Palbociclib in RB-Positive Metastat…
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