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RET oncogene
Summary
General Info
Curated Studies
Most Correlated Studies
Thyroid adenomas and carcinomas expression profiles
Lung adenocarcinoma LC-2/ad parental and ponatinib-resistant PR1 and PR2 cells
Thyroid cancer TT and MZ-CRC-1 cells treated with dinaciclib
Lung cancer and tumor-adjacent normal tissues from smokers and non-smokers
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Most Relevant Literature
Loss-of-function mutation of c-Ret causes cerebellar hypoplasia in mice with Hirschsprung disease an…
Recent developments of RET protein kinase inhibitors with diverse scaffolds as hinge binders.
Vandetanib in a Child Affected by Neurofibromatosis Type 1 and Medullary Thyroid Carcinoma with Both…
Progress and challenges in RET-targeted cancer therapy.
Targeting RET Solvent-Front Mutants with Alkynyl Nicotinamide-Based Inhibitors.
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Clinical Trials
Most Relevant Clinical Trials
Study of TPX-0046, A RET/SRC Inhibitor in Adult Subjects With Advanced Solid Tumors Harboring RET Fu…
A Study of APS03118 in Advanced Solid Tumors Harboring RET Mutations or Fusions
Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TC
Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With T…
Phase II Study With Cabozantinib in Patients With RET Positive NSCLC
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