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Raf-kinase
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Genetic Markers
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Pathway Enrichment
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Curated Studies
Most Correlated Studies
SkMel-1 and Malme3M Skin Melanoma Lines Treated with PLX4032 (Plexxikon)
Hearts with myocardium-specific expression of RKIP or a GRK-specific peptide inhibitor
Melanoma 1205Lu cells treated with AZD1152 or SNS-314 - a timecourse
Amelanocytic malignant A375 melanoma tumors resistant to vemurfenib
Colorectal cancer Caco-2et cells with dox-induced KRAS G12V mutation and with MS-275
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Literature
Most Relevant Literature
Genetic and epigenetic alterations in primary colorectal cancers and related lymph node and liver me…
Tyr phosphatase-mediated P-ERK inhibition suppresses senescence in EIA + v-raf transformed cells, wh…
Development of novel, highly potent inhibitors of V-RAF murine sarcoma viral oncogene homologue B1 (…
Ras/Raf/ERK signalling and NF1.
Exploration of genetic alterations in human endometrial cancer and melanoma: distinct tumorigenic pa…
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Clinical Trials
Most Relevant Clinical Trials
Evaluation of Pathway Modulation by Raf, MEK, & Kinase Inhibitors
An Open-Label, Non-Comparative, Phase III Study of the Raf-Kinase Inhibitor BAY 43-9006 as a Subsequ…
Interest of the 18F-DOPA-PET Imaging in Metastatic Melanoma Treated With B-RAF Inhibitors: a Pilot S…
Evaluation of a Promising New Combination of Protein Kinase Inhibitors on Organotypic Cultures of Hu…
A Trial of Trametinib and Panitumumab in RAS/RAF Wild Type Advanced Colorectal Cancer
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