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Ribonucleotide reductase
(compound)
Summary
General Info
Genetic Markers
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Curated Studies
Most Correlated Studies
Primary effusion lymphoma BCP1 cells treated with ribonucleotide reductase inhibitor triapine
Multiple myeloma NCI-H929 cells with siRNA knockdown of ribonucleotide reductases M1 and M2
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
Skin fibroblasts of patients with defective complex I (CI) oxidative phosphorylation disease
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Literature
Most Relevant Literature
Biofilm modifies expression of ribonucleotide reductase genes in Escherichia coli.
Novel pseudopeptides incorporating a benzodiazepine-based turn mimetic--targeting Mycobacterium tube…
Mechanism of assembly of the dimanganese-tyrosyl radical cofactor of class Ib ribonucleotide reducta…
Deletion of Marek's disease virus large subunit of ribonucleotide reductase impairs virus growth in …
Control of metallation and active cofactor assembly in the class Ia and Ib ribonucleotide reductases…
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Clinical Trials
Most Relevant Clinical Trials
RNR Inhibitor COH29 in Treating Patients With Solid Tumors That Are Refractory to Standard Therapy o…
GTI-2040 and Docetaxel in Treating Patients With Recurrent, Metastatic, or Unresectable Locally Adva…
The Safety and Effectiveness of Hydroxyurea and ddI Used Individually or Together in HIV-Infected Pa…
Gemcitabine and S-1 for Locally Advanced Unresectable or Metastatic Pancreatic Cancer
GTI-2040 and Gemcitabine in Treating Patients With Metastatic or Unresectable Solid Tumors
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