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Sotrastaurin
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Genetic Markers
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Curated Studies
Most Correlated Studies
Mantle cell lymphoma cell lines treated with PKC inhibitor AEB071
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
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Literature
Most Relevant Literature
Sotrastaurin, a PKC inhibitor, attenuates RANKL-induced bone resorption and attenuates osteochondral…
Protein kinase C targeting of luminal (T-47D), luminal/HER2-positive (BT474), and triple negative (H…
Protein kinase C inhibitor sotrastaurin in de novo liver transplant recipients: a randomized phase I…
Effect of miR-196a inhibition on esophageal cancer growth in vitro.
Inhibition of JAK3 and PKC via Immunosuppressive Drugs Tofacitinib and Sotrastaurin Inhibits Prolife…
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Clinical Trials
Most Relevant Clinical Trials
Sotrastaurin Acetate in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, …
Efficacy, Safety, Tolerability, and Pharmacokinetics of Sotrastaurin Combined With Tacrolimus vs. a …
Efficacy, Safety, Tolerability, Pharmacokinetics of Sotrastaurin-tacrolimus vs. Mycophenolic Acid-ta…
CAEB071 Thorough QTc Study in Healthy Volunteers
A Phase Ib/II Study of AEB071 and MEK162 in Adult Patients With Metastatic Uveal Melanoma
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