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Spinocerebellar ataxia
(phenotype)
Summary
General Info
Genetic Markers
Most Correlated Genes
Most Correlated SNPs
FGF14
TDP1
GYPB
SCAX5
VPS41
No SNPs found
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Pathway Enrichment
Most Correlated Biogroups
CAGTGTT_MIR141_MIR200A
FXR_Q3
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN
GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_DC_DN
Concanavalin A-like lectin/glucanase domain superfamily
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Curated Studies
Most Correlated Studies
Friedreich’s ataxia induced pluripotent stem cells
Lymphoblastoid cell lines of Spinocerebellar Ataxia Type 28 patients (mutated AFG3L2)
Cerebella, midbrains and livers from 6mo, 12mo and 24mo old ATXN2 knockout mice
Neural progenitors from Friedreich ataxia patient iPSCs (induced pluripotent stem cells)
Cerebella from SCA6 MPI 118Q/118Q and MPI 11Q/11Q knockin spinocerebellar ataxia mouse models
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Literature
Most Relevant Literature
Myelinating Glia: Potential Therapeutic Targets in Polyglutamine Spinocerebellar Ataxias.
Rating scales and biomarkers for CAG-repeat spinocerebellar ataxias: Implications for therapy develo…
Spinocerebellar ataxia clinical trials: opportunities and challenges.
Composite autonomic severity scoring in spinocerebellar ataxia type 1 and 2.
Single-Tube Screen for Rapid Detection of Repeat Expansions in Seven Common Spinocerebellar Ataxias.
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Clinical Trials
Most Relevant Clinical Trials
Dalfampridine and Gait in Spinocerebellar Ataxias
Identification of Biomarkers in Spinocerebellar Ataxia 3
Study of CAD-1883 for Spinocerebellar Ataxia
Measuring Neurological Impairment and Functional Visual Assessment In Spinocerebellar Ataxias
Efficacy Of Oral Trehalose In Spinocerebellar Ataxia 3
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