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QuickView for Stavudine (compound)


Genetic Markers

Most Correlated Genes

  1. Abcb1b
  2. CYP1A1
  3. Fam25c
  4. DBP
  5. STAC3
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Pathway Enrichment

Most Correlated Biogroups

  1. PILON_KLF1_TARGETS_DN
  2. heterocyclic compound binding
  3. organic cyclic compound binding
  4. PUJANA_BRCA1_PCC_NETWORK
  5. heterocycle metabolic process
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Curated Studies

Most Correlated Studies

  1. Drug Matrix In Vivo Toxicogenomic Study - Rat Liver [Affymetrix]
  2. Drug Matrix In Vitro Toxicogenomic Study - Rat Hepatocytes [Affymetrix]
  3. Drug Matrix In Vitro Toxicogenomic Study - Rat Hepatocytes [Codelink]
  4. Drug Matrix In Vivo Toxicogenomic Study - Rat Heart [Codelink]
  5. Drug Matrix In Vivo Toxicogenomic Study - Rat Liver [Codelink]
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Literature

Most Relevant Literature

  1. Polyfluoroaromatic stavudine (d4T) ProTides exhibit enhanced anti-HIV activity.
  2. Elucidation of binding mechanism and identification of binding site for an anti HIV drug, stavudine …
  3. The artifactual nature of stavudine binding to human serum albumin. A fluorescence quenching and iso…
  4. Risk factors of treatment-limiting anemia after substitution of zidovudine for stavudine in HIV-infe…
  5. Stavudine induced acute necrotizing pancreatitis with tetany in a pediatric patient.
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Clinical Trials

Most Relevant Clinical Trials

  1. Dose Optimisation of Stavudine for the Treatment of HIV Infection
  2. A Study of Efavirenz in Combination With Stavudine and Didanosine
  3. Evaluation of Viral Efficacy and Safety of a Reduced Dose of Stavudine (d4T): THE PHOENIX STUDY
  4. Effects of Uridine Supplementation on Metabolic Side Effects of Stavudine and Zidovudine
  5. Differences Between Stavudine and Tenofovir Each Combined With Lamivudine and Efavirenz in SA HIV-in…
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