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TCPOBOP
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NextBio Summary
General Info
Genetic Markers
Most Correlated Genes
GSTM3
CYP2C18
CYP2B6
CDC20
Akr1b7
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Pathway Enrichment
Most Correlated Biogroups
cell cycle
endoplasmic reticulum
cytosol
organic cyclic compound binding
heterocyclic compound binding
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Curated Studies
Most Correlated Studies
Liver of CAR KO and KO with human CAR rescue treated with different ligands
Primary hepatocytes treated with non-genotoxic carcinogens or non-carcinogens
Embryonic stem cells treated with non-genotoxic carcinogens or non-carcinogens
Livers exposed to CAR agonist TCPOBOP or PXR agonist pregnenolone 16alpha-carbonitrile
Liver from mice treated with PXR or CAR ligands
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Literature
Most Relevant Literature
Impact of CAR Agonist Ligand TCPOBOP on Mouse Liver Chromatin Accessibility.
Identification of Candidate Target Cyp Genes for microRNAs Whose Expression Is Altered by PCN and TC…
Expression of c-jun is not mandatory for mouse hepatocyte proliferation induced by two nuclear recep…
The primary mitogen (TCPOBOP)-induced hepatocyte proliferation is resistant to transforming growth f…
Yap is crucial for CAR-driven hepatocyte proliferation, but not for induction of drug metabolism gen…
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There were no clinical trials for TCPOBOP
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