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THO complex
(biogroup)
Summary
General Info
Body Atlas
Most Correlated Tissues
No tissues found
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Disease Atlas
Most Correlated Diseases
Vesicular stomatitis Indiana virus disease
Placental insufficiency
Listeriosis
Poisoning by drug AND/OR medicinal substance
Toxic nephropathy
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Pharmaco Atlas
Most Correlated Compounds
5-(6)-carboxyfluorescein diacetate succinimidyl ester
Floxuridine
enterotoxin F, Staphylococcal
SN-38
P79 protein, human
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Knockdown Atlas
Most Correlated Gene Perturbations
comr
MIR489
CYP4Z2P
SEPT4
TIRAP
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Curated Studies
Most Correlated Studies
The Immunological Genome Project - Immune cell lineage differentiation and maturation
Expression profile of HDAC treated LNCaP cells
L1000 CMAP - Colorectal cancer HT29.311 cells with CRISPR-targeted gene knockouts
L1000 CMAP - Amelanotic malignant melanoma of skin A375 cells treated with ligand perturbagens
L1000 CMAP - Neural progenitor NPC.CAS9 cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
piRNA-independent transposon silencing by the Drosophila THO complex.
THO complex deficiency impairs DNA double-strand break repair via the RNA surveillance kinase SMG-1.
Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex.
The THO Complex Non-Cell-Autonomously Represses Female Germline Specification through the TAS3-ARF3 …
Sumoylation of the THO complex regulates the biogenesis of a subset of mRNPs.
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Clinical Trials
Most Relevant Clinical Trials
MRA and ARB Treatment in Screening of Primary Aldosteronism
Short-course Regimens for the Treatment of Pulmonary Tuberculosis
A Mobile Application to Improve Case-management and Patient's Functioning in First Episode Psychosis
Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients With Chronic Kidney Disease, on …
Phase III Trial BI 695502 Plus Chemotherapy vs. AvastinĀ® Plus Chemotherapy in Patients With Lung Can…
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