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QuickView for TMC1 (gene)


Body Atlas

Most Correlated Tissues

  1. Transverse colon
  2. Rectum colon
  3. Parotid gland
  4. Ascending colon
  5. Sigmoid colon
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Disease Atlas

Most Correlated Diseases

  1. Sensorineural hearing loss
  2. Infectious disease of lung
  3. Lower respiratory tract infection
  4. Interstitial lung disease
  5. Bacterial sepsis of newborn
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Pharmaco Atlas

Most Correlated Compounds

  1. MRK 003
  2. testosterone 17 beta-cypionate
  3. perfluorobutane sulfonate
  4. Bucladesine
  5. Cannabidiol
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. TMEM173
  2. FOXP1
  3. ETV2
  4. CDK7
  5. HHEX
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. Mutation-agnostic RNA interference with engineered replacement rescues Tmc1-related hearing loss.
  2. Optimized AAV Vectors for TMC1 Gene Therapy in a Humanized Mouse Model of DFNB7/11.
  3. Deafness mutation D572N of TMC1 destabilizes TMC1 expression by disrupting LHFPL5 binding.
  4. Single and Dual Vector Gene Therapy with AAV9-PHP.B Rescues Hearing in Tmc1 Mutant Mice.
  5. Tmc proteins are essential for zebrafish hearing where Tmc1 is not obligatory.
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Clinical Trials

Most Relevant Clinical Trials

  1. Study of Cerebral Activation During Different Rehabilitation Tasks in Mirror Therapy in Healthy Subj…
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