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QuickView for TORC1
Most Correlated Studies
- Hematopoeitic stem and progenitor cells: specific TORC1 knockout
- Hematopoietic progenitor cells with induced RPTOR-knockout
- S. pombe cells with isp7+ knockout
- S. cerevisiae exponential cultures; nitrogen sources shifted between proline and glutamine
- S.cerevisiae gene expression under nutrient deprivation in snf1 and tor1 null strains
Most Relevant Literature
- Non-dikarya fungi share the TORC1 pathway with animals, not with Saccharomyces cerevisiae.
- Vacuoles provide the source membrane for TORC1-containing signaling endosomes.
- The Greatwall kinase Rim15 promotes microautophagy and microlipophagy under the control of TORC1.
- Curcumin Inhibits TORC1 and Prolongs the Lifespan of Cells with Mitochondrial Dysfunction.
- Distinct TORC1 signalling branches regulate Adc17 proteasome assembly chaperone expression.
Most Relevant Clinical Trials
- Phase I Study of Palomid 529 a Dual TORC1/2 Inhibitor of the PI3K/Akt/mTOR Pathway for Advanced Neov…
- Dual TORC1/TORC2 Inhibitor ATG-008 (CC-223) in HBV Positive Advanced Hepatocellular Carcinoma (HCC) …
- A Open-Label, Multiple Ascending Dose Study of DS-3078a, an Oral TORC1/2 Kinase Inhibitor, in Subjec…
- TORC1/2 Inhibitor MLN0128 and Bevacizumab in Treating Patients With Recurrent Glioblastoma or Advanc…
- Neoadjuvant Rapamycin in Patients Undergoing Radical Cystectomy
