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TPP1
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Body Atlas
Most Correlated Tissues
Granulocyte-macrophage progenitor cell of bone marrow
Macrophage of peripheral blood
Microglial cell
Monocyte of peripheral blood
Myeloid cells of peripheral blood
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Disease Atlas
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Cerebral lipidosis
Caseating tuberculoid granuloma
Irritable bowel syndrome
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Indoprofen
oxidized low density lipoprotein
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tetrahydropalmatine
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Most Correlated Gene Perturbations
hsa-miR-365a-3p
FNIP1
SMARCD1
GJB2
MIR107
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Literature
Most Relevant Literature
A mouse mutant deficient in both neuronal ceroid lipofuscinosis-associated proteins CLN3 and TPP1.
Tripeptidyl Peptidase 1 Regulates Human Trophoblast Cell Proliferation Implying a Role in Placentati…
Generation of pathogenic TPP1 mutations in human stem cells as a model for neuronal ceroid lipofusci…
Elevated levels of tripeptidyl peptidase 1 do not ameliorate pathogenesis in a mouse model of Alzhei…
TPP1 Delivery to Lysosomes with Extracellular Vesicles and their Enhanced Brain Distribution in the …
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Clinical Trials
Most Relevant Clinical Trials
Examining Developmental Outcomes of Children Diagnosed With CLN2 Disease
A First-in-Human Study in Pediatric Patients With Ocular CLN2 Disease
Longitudinal Assessment of Atypical Tripeptidyl Peptidase 1 Enzyme Deficiency Patients
Natural History and Longitudinal Clinical Assessments in NCL / Batten Disease, the International DEM…
A Safety, Tolerability, and Efficacy Study of Intracerebroventricular BMN 190 in Pediatric Patients …
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