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QuickView for TREM2 (gene)


Body Atlas

Most Correlated Tissues

  1. Microglial cell
  2. Skeletal muscle psoas
  3. Olfactory bulb
  4. Tongue
  5. Nodose nucleus
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Disease Atlas

Most Correlated Diseases

  1. Bone cyst
  2. High fat diet
  3. Stachybotryotoxicosis
  4. Ischemia
  5. Injury of external ear
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Pharmaco Atlas

Most Correlated Compounds

  1. Bleomycin
  2. Smoke
  3. Chemokine CCL17
  4. Exotoxins
  5. Quercetin
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. TREM2
  2. GFI1B
  3. PSEN1
  4. CCNT1
  5. MIR7-1
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. Identification and Validation of TREM2 in Intracranial Aneurysms.
  2. Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in …
  3. TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodege…
  4. The Jekyll and Hyde of TREM2.
  5. Treadmill exercise improve recognition memory by TREM2 pathway to inhibit hippocampal microglial act…
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Clinical Trials

Most Relevant Clinical Trials

  1. A Study of PY314 in Subjects With Advanced Solid Tumors
  2. Gut Microbiota and Parkinson's Disease
  3. Simufilam (PTI-125), 100 mg, for Mild-to-moderate Alzheimer's Disease Patients
  4. Randomized I/II Phase Study of ALZT-OP1 Combination Therapy in Alzheimer's Disease and Normal Health…
  5. Application of Diffusion Tensor Imaging in Alzheimer's Disease :Quantification of White Matter Micro…
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