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Tetrodotoxin
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
ADCYAP1
EGR4
TCIM
TRIM59
NF1
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Pathway Enrichment
Most Correlated Biogroups
EGF-like calcium-binding domain
EGF-like domain
EGF-like, conserved site
EGF-like calcium-binding, conserved site
EGF-type aspartate/asparagine hydroxylation site
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Curated Studies
Most Correlated Studies
Cerebellar after ventral hippocampal lesion or tetrodotoxin disruption, or neuroleptics trea
Neurotoxin tetrodotoxin (TTX) withdrawal induced neuronal gene expression activity
Hippocampal neurons in culture with TET3 shRNA and/or bicuculline or tetrodotoxin treated
Ipsi- and contralateral cochlear nucleus after TTX exposure to block activity in 8th nerve
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Literature
Most Relevant Literature
An Oxidative Dearomatization Approach to Tetrodotoxin via a Masked ortho-Benzoquinone.
Synthesis of the 8-Deoxy Analogue of 4,9-Anhydro-10-hemiketal-5-deoxy-tetrodotoxin, a Proposed Biosy…
Tissue accumulation of tetrodotoxin (TTX) and analogues in trumpet shell Charonia lampas.
Tetrodotoxins in the flatworm Planocera multitentaculata.
Sea temperature influences accumulation of tetrodotoxin in British bivalve shellfish.
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Clinical Trials
Most Relevant Clinical Trials
Tetrodotoxin Open-label Efficacy and Safety Continuation Study
Safety & Efficacy Study of Subcutaneous Tetrodotoxin for Moderate to Severe Inadequately Controlled …
The Purpose of This Study is to Determine if Tetrodotoxin (TTX) is Effective in the Treatment of Pai…
A Phase 1, Single Ascending Dose, Randomized, Double-Blind, Placebo and Positive Controlled Study to…
Comparison Study of Liquid and Lyophilized Formulations of Subcutaneous Tetrodotoxin (TTX) in Health…
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