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QuickView for Tie2 (gene)


Body Atlas

Most Correlated Tissues

  1. Superior cervical ganglion
  2. Atrioventricular node
  3. Ciliary ganglion
  4. Appendix
  5. Skeletal muscle psoas
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Disease Atlas

Most Correlated Diseases

  1. Venous malformation
  2. Neurocutaneous syndrome
  3. Zika virus disease
  4. Vascular disorder
  5. Tinea pedis
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Pharmaco Atlas

Most Correlated Compounds

  1. Todralazine
  2. graveoline
  3. Carticaine
  4. Trypsin
  5. Cholesterol
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. PAICS
  2. BCAR1
  3. BAG3
  4. MTAP
  5. IMPA2
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. Angpt2/Tie2 autostimulatory loop controls tumorigenesis.
  2. Tek (Tie2) is not required for cardiovascular development in zebrafish.
  3. Structural insights into the clustering and activation of Tie2 receptor mediated by Tie2 agonistic a…
  4. Endothelial deletion of EPH receptor A4 alters single-cell profile and Tie2/Akap12 signaling to pres…
  5. Identification of specific Tie2 cleavage sites and therapeutic modulation in experimental sepsis.
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Clinical Trials

Most Relevant Clinical Trials

  1. Validation of Tie2 as the First Tumour Vascular Response Biomarker for VEGF Inhibitors: VALTIVE1
  2. Evaluation of the Predictive Value of Blood Levels of Angiopoietin 1 and Endothelial Internal Tunica…
  3. A Study of ARRY-614 in Patients With Low or Intermediate-1 Risk Myelodysplastic Syndrome
  4. A Study of ARRY-614 in Patients With Low or Intermediate-1 Risk Myelodysplastic Syndromes
  5. ESK981 in Treating Patients With Metastatic Castrate-Resistant Prostate Cancer
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