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WP1066
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Summary
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Genetic Markers
Most Correlated Genes
ACTB
Rn18s
9530002B09Rik
OLFM4
5430419D17Rik
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Pathway Enrichment
Most Correlated Biogroups
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN
TRAVAGLINI_LUNG_PROLIFERATING_MACROPHAGE_CELL
HSIAO_HOUSEKEEPING_GENES
RUBENSTEIN_SKELETAL_MUSCLE_MYELOID_CELLS
RUBENSTEIN_SKELETAL_MUSCLE_SATELLITE_CELLS
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Curated Studies
Most Correlated Studies
Prostate cancer mouse models treated with different compounds
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Literature
Most Relevant Literature
WP1066, a small molecule inhibitor of STAT3, chemosensitizes paclitaxel-resistant ovarian cancer cel…
Identification of WP1066, an inhibitor of JAK2 and STAT3, as a KV 1.3 potassium channel blocker.
A first-in-human Phase I trial of the oral p-STAT3 inhibitor WP1066 in patients with recurrent malig…
WP1066 induces cell death in a schwannomatosis patient-derived schwannoma cell line.
Inhibition of STAT3 signal pathway recovers postsynaptic plasticity to improve cognitive impairment …
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AflacST1901: Peds WP1066
WP1066 and Radiation Therapy in Newly Diagnosed Glioblastoma Patients
STAT3 Inhibitor WP1066 in Treating Patients With Recurrent Malignant Glioma or Progressive Metastati…
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