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Wy-14643
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Summary
General Info
Genetic Markers
Most Correlated Genes
PDK4
Acot1
ACOT2
VNN1
FABP4
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Pathway Enrichment
Most Correlated Biogroups
HSIAO_LIVER_SPECIFIC_GENES
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP
MOOTHA_MITOCHONDRIA
MODULE_23
MOOTHA_HUMAN_MITODB_6_2002
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Curated Studies
Most Correlated Studies
Hepatocytes treated with non-genotoxic carcinogens
HepG2 cells treated with genotoxic and non-genotoxic agents
Livers of CD-1 mice treated with genotoxic, non-genotoxic or non-hepatocarcinogens
Primary hepatocytes treated with non-genotoxic carcinogens or non-carcinogens
Embryonic stem cells treated with non-genotoxic carcinogens or non-carcinogens
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Literature
Most Relevant Literature
Chronic Treatment With WY-14643 Induces Tumorigenesis and Triglyceride Accumulation in Mouse Livers.
PPARα agonist WY-14,643 enhances ethanol metabolism in mice: Role of catalase.
PPARα Agonist WY-14643 Relieves Neuropathic Pain through SIRT1-Mediated Deacetylation of NF-κB.
PPARα agonist WY-14,643 induces adipose atrophy and fails to blunt chronic ethanol-induced hepatic f…
PPARα agonist WY-14,643 induces the PLA2/COX-2/ACOX1 pathway to enhance peroxisomal lipid metabolism…
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Clinical Trials
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There were no clinical trials for Wy-14643
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