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YAP1 protein
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General Info
Curated Studies
Most Correlated Studies
Breast cancer MDA-MB-231-LM2-4 cells TGF-b1 treated and depleted of TAZ/YAP or TEAD1/2/3/4
Intestinal epithelia from mice with gut-specific YAP knockout and R-Spondin1 treated
Colorectal cancer HCT116 cells with siRNA knockdown of Yes-associated protein 1
Hepatocellular carcinoma HLE cells with YAP/TAZ or ATF4 knockdown and treated with Sorafenib
Hepatic adenocarcinoma cells SK-Hep1 with siRNA targeting YAP1 and TAZ
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Literature
Most Relevant Literature
Long term exposure of saxitoxin induced cognitive deficits and YAP1 cytoplasmic retention.
YAP1 is essential for malignant mesothelioma tumor maintenance.
YAP1 suppression inhibits autophagy and improves the efficacy of anti-PD-1 immunotherapy in hepatoce…
The oncogenic role of NF1 in gallbladder cancer through regulation of YAP1 stability by direct inter…
The YAP1-TEAD axis promotes autophagy against intracellular Staphylococcus aureus in vitro.
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Clinical Trials
Most Relevant Clinical Trials
Tissue Predictors of Abiraterone Benefit
A Study of ION537 in Patients With Molecularly Selected Advanced Solid Tumors
Testing a New Anti-cancer Drug Combination, Entinostat and GSK525762C, for Advanced and Refractory S…
Testing A New Anti-cancer Drug Combination, Entinostat and ZEN003694, for Advanced and Refractory So…
Selective Treatment According to Molecular Subtype of Prostate Cancer
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