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anthracyclines
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
CDKN1A
FOS
TOP2A
ALAS2
HBB
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Pathway Enrichment
Most Correlated Biogroups
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN
DODD_NASOPHARYNGEAL_CARCINOMA_DN
regulation of nitrogen compound metabolic process
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP
FISCHER_DREAM_TARGETS
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Curated Studies
Most Correlated Studies
Breast tumors with pathologic complete response (pCR) or residual disease (RD) upon chemotherapy
B cell lymphoma gene expression in response to the senescence-inducing anti-cancer agent adriamycin
DNA damage in widtype and RORa mutant mice
Breast cancer MCF-7 cells with RBM38 knockdown and doxorubicin induced stress
OV90 sublines selected for resistance to cisplatin, doxorubicin and paclitaxel
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Literature
Most Relevant Literature
Upcycling the anthracyclines: New mechanisms of action, toxicology, and pharmacology.
Doxorubicin and other anthracyclines in cancers: Activity, chemoresistance and its overcoming.
Anthracyclines inhibit SARS-CoV-2 infection.
Anthracyclines: biosynthesis, engineering and clinical applications.
Anthracyclines versus No Anthracyclines in the Neoadjuvant Strategy for HER2+ Breast Cancer: Real-Wo…
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Clinical Trials
Most Relevant Clinical Trials
Spironolactone Against Anthracycline-induced Cardiomyopathy
Markers of Anthracycline-Related Cardiac Muscle Injury
Ivabradine to Prevent Anthracycline-induced Cardiotoxicity
Efficacy of TopotectTM (Dexrazoxane) for Accidental Extravasation of Anthracyclines
Assessment of Global Longitudinal Strain for the Prediction of Anthracycline Induced Cardiotoxicity
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