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QuickView for antiparkinsonian agents (compound)


Genetic Markers

Most Correlated Genes

  1. COMT
  2. PDK4
  3. GRIN3A
  4. SERPINB2
  5. DRD2
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Pathway Enrichment

Most Correlated Biogroups

  1. response to organic substance
  2. regulation of nitrogen compound metabolic process
  3. cell periphery
  4. PILON_KLF1_TARGETS_DN
  5. organic cyclic compound metabolic process
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Curated Studies

Most Correlated Studies

  1. Drd2 and Drd1a spiny projection neurons parkinsonian treated with high and low dose DOPA
  2. Dopamine Signaling in Parkinson disease model
  3. Cortical neurons exposed to excitotoxic NMDA and potentially neuroprotective compounds
  4. B-cell lymphoma cell lines treated by 92 FDA approved compounds - a timecourse
  5. Cerebrocortical cells treated with blood-brain barrier penetrant clinic-tested drugs
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Literature

Most Relevant Literature

  1. Mechanisms of Antiparkinsonian Anticholinergic Therapy Revisited.
  2. Antidopaminergic-Antiparkinsonian Medication Prescribing Cascade in Persons with Alzheimer's Disease…
  3. Identification of antiparkinsonian drugs in the 6-hydroxydopamine zebrafish model.
  4. The risk of melanoma with rasagiline compared with other antiparkinsonian medications: A retrospecti…
  5. Oral antiparkinsonian treatments, nursing practices in Ehpad].
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Clinical Trials

Most Relevant Clinical Trials

  1. A Study to Evaluate SAGE-217 in Participants With Parkinson's Disease
  2. Anticholinergic Burden in Schizophrenia
  3. A Study Comparing Efficacy of Levodopa-Carbidopa Intestinal Gel/Carbidopa-Levodopa Enteral Suspensio…
  4. Sequence Effect in Parkinson's Disease
  5. Botulinum Toxin Type A for Foot Dystonia-associated Pain in Parkinson's Disease
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