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belinostat
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Summary
General Info
Genetic Markers
Most Correlated Genes
MAL
CFD
LCN2
LPL
RAB11FIP1
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Pathway Enrichment
Most Correlated Biogroups
regulation of nitrogen compound metabolic process
vesicle
organic cyclic compound binding
heterocyclic compound binding
cytosol
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Curated Studies
Most Correlated Studies
Pancreatic cell lines treated with chromatin-targeting small molecules
Mononuclear cells from blood of belinostat non-responder and responder AML patients
Lung squamous cell carcinoma cells treated with PXD101 (belinostat)
Decitabine and PXD101 treated Cisplatin sensitive and resistant ovarian cancer cells
Neuroepithelial progenitors differentiated from ESCs and treated with toxicants
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Literature
Most Relevant Literature
Phase 1 study of belinostat and adavosertib in patients with relapsed or refractory myeloid malignan…
Belinostat (PXD101) resists UVB irradiation-induced cellular senescence and skin photoaging.
Anticancer clinical efficiency and stochastic mechanisms of belinostat.
Mutant Isocitrate Dehydrogenase 1 Expression Enhances Response of Gliomas to the Histone Deacetylase…
Final Report on Clinical Outcomes and Tumor Recurrence Patterns of a Pilot Study Assessing Efficacy …
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Clinical Trials
Most Relevant Clinical Trials
Belinostat in Treating Patients With Myelodysplastic Syndromes
Carfilzomib Plus Belinostat in Relapsed/Refractory NHL
MRSI to Predict Response to RT/TMZ ± Belinostat in GBM
To Evaluate Safety and Pharmacokinetics of Belinostat in Patients Who Have Mild, Moderate and Severe…
Establish the PK of Belinostat in Patients With Wild-type, Heterozygous, and Homozygous UGT1A1*28 Ge…
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